Very much so. I-GIF igqityiwe kwi-256-imibala yengqokelela yezixhobo ene-bit enye (esebenzayo/ekhubazekileyo) yobunzulu obubonakalayo kwaye akukho lpha echaphazelekayo, oko kukuthi, imifanekiso ibanda kwaye i-dither kuyo. That determines both the headroom available and whether the saving costs you anything in fidelity.
Yes — ingqokelela yezixhobo inikezelwa kumfanekiso ophilayo wonke, ngoko naliphi na utshintsho kwisakhelo sithethwa ngokuchasene namabala onke afunekayo kwisakhelo. It is worth knowing before you overwrite an original you might need again.
Yintoni impazamo eqhelekileyo xa uxinzelela GIF animations?